Harry Boniface Prabhu is an Indian quadriplegic wheelchair tennis player, one of the pioneers of the sport in Indiaand a medal winner at the 1998 World Championships.He was awarded the Padma Shree, the fourth highest civilian award, by the Government of India, in 2014.

Boniface Prabhu was born to Harry J. Prabhu and Fathima Prabhu, on 14 May 1972, at Bangalore, in the south Indian state ofKarnataka, as a normal child like his two brothers, Jerry and George. The tragedy struck at the age of four, when a blotched lumbar puncture made him a quadriplegic for the rest of his life. However, he was brought up by his parents as a normal boy, sending him to institutions for normal children which helped the young Boniface to take up life as any competitive person would.

Boniface Prabhu is the founder of a trust, Boniface Prabhu Wheelchair Tennis Academy, based in Bangalore, with the aim of promoting the physically and intellectually challenged people and providing them with opportunities to nurture their talents. The Academy provides free sports training to differently enabled people.

Boniface is married to Christina and the couple has a daughter, Simone Diya.

Though Boniface's principal claim to fame is wheelchair tennis, he has excelled in other disciplines, too. He has represented India, at International events, in six disciplines, over 50 times. These include athletics, shot put, badminton, javelin throw, table tennis,shooting and discus throw, apart from wheelchair tennis. His foray into international sports was at the 1996 World Wheelchair Games, UK where he won gold medal in shot put and silver medal in discus throw. Two years later, he repeated the feat at the 1998 Paralympics World Championships, participating in javelin, shot put and discus throws. He is the first Indian to win a medal in the International Paralympic Games.